625 Role of eutectic mixture of ceramides for reconstruction of stratum corneum intercellular lipid model
نویسندگان
چکیده
منابع مشابه
Novel lipid mixtures based on synthetic ceramides reproduce the unique stratum corneum lipid organization.
Lipid lamellae present in the outermost layer of the skin protect the body from uncontrolled water loss. In human stratum corneum (SC), two crystalline lamellar phases are present, which contain mostly cholesterol, free fatty acids, and nine types of free ceramides. Previous studies have demonstrated that the SC lipid organization can be mimicked with model mixtures based on isolated SC lipids....
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15 صفحه اولEpidermal sphingomyelins are precursors for selected stratum corneum ceramides.
Epidermal ceramides (Cer) comprise a heterogeneous family of seven species, including two unique omega-hydroxylated Cer, that are key components of the stratum corneum (SC) intercellular lamellar membranes responsible for the epidermal permeability barrier. Although both glucosylceramide (GlcCer) and the phospho-sphingolipid sphingomyelin (SM) are potential precursors of SC Cer, based on report...
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[Transition processes in Stratum corneum model lipid membranes with a mixture of free fatty acids].
The hydration of model membranes based on ceramide 6 with a mixture of free fatty acids the most commonly encountered the native lipid matrix of Stratum corneum, the outermost layer of the mammalian skin has been studied by neutron diffraction. Membrane hydration with water vapour at a temperature of 25 degrees C is characterized by a small increase in the repeat distance delta d0 = 1.0 A, whic...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2018
ISSN: 0022-202X
DOI: 10.1016/j.jid.2018.03.634